Which of the following conditions is characterized by congenital absence of thyroid function?

Cretinism is a condition resulting from congenital hypothyroidism, which is characterized by the absence or severe deficiency of thyroid hormone production from birth. This lack of thyroid function can lead to a variety of developmental issues and physical manifestations, including severe cognitive deficits, growth retardation, and characteristic physical features. In infants, thyroid hormones are critical for normal growth and neurological development, and without adequate levels, the consequences can be profound.

Myxedema refers to severe hypothyroidism occurring in adulthood and is not associated with congenital absence of thyroid function. Hyperthyroidism, on the other hand, involves an overproduction of thyroid hormones, and Addison's disease is related to adrenal insufficiency and has no direct correlation with thyroid function. Therefore, the defining traits of cretinism highlight its specific association with the congenital absence of thyroid function, making it the correct answer.